This webinar was recorded on 17-18 September 2020.
Part of the IPEC Europe Excipient Conference webinar series, organised in cooperation with APV GmbH.
DESCRIPTION
Continuous Manufacturing (CM) involves the continuous feeding of input materials into, transformation of in-process materials within, and removal of output materials from a system. Therefore, the consistency of excipient properties to be feed into these processes is of great importance in determining appropriate formulation and process control strategies. In addition, typically there is a need to limit the number of feeders in a continuous manufacturing process which means that the number of excipients may need to be limited as well which means that there will be certain advantages which can be achieved from formulating with high performance excipients, excipient mixtures or co-processed excipients which are designed for purpose. This presentation will provide an overview of the importance of understanding excipient properties and typical variability on products made using continuous manufacturing. There will also be a discussion concerning what design criteria should be considered when developing excipients and selecting them for a CM formulation. The developing regulatory landscape concerning CM and appropriate excipients (including novel excipients) for use in CM will also be discussed.
