A distribution procedure to ensure that the stock with the earliest expiry date is distributed and/or utilized before an identical stock item with a later expiry date is distributed and/or utilized. [3, 18]
Estimated Daily Intake
European Directorate for the Quality of Medicines. 
Earliest Expiry/First Out Principle Concept
An expression of the degree to which activities have produced the effects planned. 
The relationship between the results of activities and the corresponding effort expended in terms of money, resources and time. 
Excipient Information Package
A document that is stored on a computer in an electronic file such as: Portable Document Format (PDF), scanned image (TIF, JPEG, etc.) or Microsoft application such as Word, Excel, or Access.
A tool or process which provides the means to achieve an objective. (ICH Q10) 
Lipopolysaccharides (LPS), also known as lipoglycans and endotoxin, are large molecules consisting of a lipid and a polysaccharide found in the outer membrane of Gram-negative bacteria, and elicit strong immune responses in animals. Lipopolysaccharides may be released on destruction of the bacteria, and that the immunogenic response leads to an increase in body temperature.
The implements used in the manufacture of an excipient. 
A test that determines the equivalence between the multisource product and the comparator product using in vivo and/or in vitro approaches. 
see Estimated Daily Intake 
The estimated maximum daily intake (I) of the dosage form (tablets per day) and the concentration (C) of the excipient in each dosage form (mg/tablet) divided by the body weight (BW) in kilograms 
EDI = I * C
Substances other than the API which have been appropriately evaluated for safety and are intentionally included in a drug delivery system. [1, 3, 4, 6]
An IPEC initiative to provide standards for the exchange of data between excipient suppliers and excipient users. The EIP is comprised of the Site Quality Overview, Product Regulatory Datasheet, and Site and Supply Chain Security Overview. IPEC’s Standardized Excipient Information Protocol User Guide provides information on the preparation of the EIP documents. 
Development, manufacture, launch and sale of an excipient with the quality attributes appropriate to meet the needs of internal customers, pharmaceutical users, regulatory authorities, health care professionals, and patients.
Elements of the EIP documents that should be included and addressed in the EIP documents. 
The duration, normally expressed in months or years from the date of manufacture, within which the excipient can continue to be used. 
The date designating the time during which the excipient is expected to remain within specifications and after which it should not be used. [1, 3, 4, 6]
Products which are formulated to make the drug available over an extended period after administration. 
An impurity arising from any source extraneous to the manufacturing process.